ANTIBACTERIAL ACTIVITY OF CELERY LEAVES (APIUM GRAVEOLENS L.) FORMULATED IN TOOTHPASTE AGAINST STREPTOCOCCUS MUTANS

ERZA, GENATRIKA and FITA, SATRIANI and INDRI, HAPSARI (2019) ANTIBACTERIAL ACTIVITY OF CELERY LEAVES (APIUM GRAVEOLENS L.) FORMULATED IN TOOTHPASTE AGAINST STREPTOCOCCUS MUTANS. ARTIKEL JURNAL.

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Abstract

Objective: The objective of this research was to determine the antibacterial activity of the toothpaste from an extract of celery leaves on Streptococcus mutans. Methods: The toothpaste was formulated with various concentrations of celery leaves, F1 with concentration of extract (6.25%), F2 (12.5%), and F3 (25%). Each formula was tested the physical characteristics and antibacterial activity toward S. mutans. The antibacterial activity was determined by the agar well diffusion method using brain heart infusion agar plates. Furthermore, the antibacterial activities were assessed by the presence or absence of inhibition zones after the plates were incubated at 37°C for 24 h. Results: The results from this test illustrate that all toothpastes under study at various concentrations of celery leaves extract exhibited antibacterial activity. Maximum inhibition zone in antibacterial activity test was shown by F2 (12.5%). Therefore, we can use these toothpastes as natural antibacterial on prevention of dental caries caused S. mutans. Conclusion: The toothpaste from an extract of celery leaves showed significant antibacterial activity against S. mutans.

Item Type: Article
Uncontrolled Keywords: Streptococcus mutans, Celery leaves, Toothpaste, Apium graveolens, Inhibition zone
Subjects: Artikel Jurnal
Divisions: Artikel Jurnal
Depositing User: Super Admin Digilib
Date Deposited: 11 Aug 2020 04:04
Last Modified: 11 Aug 2020 04:04
URI: http://digitallibrary.ump.ac.id/id/eprint/825

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