EFFECT OF ETHANOLIC EXTRACT OF Annona muricata L SEEDS POWDER TO DECREASE BLOOD GLUCOSE LEVEL OF WISTAR MALE RATS WITH GLUCOSE PRELOAD

Rian, Ulva Rizki Hasanah and Elza, Sundhani and Nunuk, Aries Nurulita (2019) EFFECT OF ETHANOLIC EXTRACT OF Annona muricata L SEEDS POWDER TO DECREASE BLOOD GLUCOSE LEVEL OF WISTAR MALE RATS WITH GLUCOSE PRELOAD. REPORT OF THE PLAGIARISM CHECK.

	Text (Peer Review) PEER REVIEW-Effect of Ethanolic Extract of Annona Muricata.pdf Download (1MB)
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Abstract

Based on data from World Health Organization (WHO) diabetes mellitus was the direct cause of death of 1.5 million people, more than 80% of deaths due to diabetes occurs in middle-income countries and low (WHO, 2014). According to the Basic Health Research (Riskesdas) in 2013, the incidence of diabetes mellitus in Indonesia increased by two times greater than in 2007. Annona muricata L is used as a traditional medicine to lower blood glucose levels with contain tannin, phytosterols, calcium oxalate, alkaloids murisin (Arief and Hariana, 2006), flavonoids and essential oils (Surbakti, 1994). Flavonoid compounds have an important role in the prevention of diabetes and its complications (Jack, 2012). Previous research showed that bark of plants soursop has a most excellent efficacy compared with the roots and leaves of the Annona muricata L in lowering blood glucose levels in male rats induced streptozozin (Rahmawati, 2014). This study aimed to examine the effect of ethanolic extract of Annona muricata L. seeds powder on decreasing blood glucose level in wistar strain male rat with glucose loading.

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