Antibacterial activity of Allium sativum L. cream formulation against Propionibacterium acnes and Staphylococcus epidermidis

Erza, Genatrika and Saripah, Ya-Koh and Indri, Hapsari (2020) Antibacterial activity of Allium sativum L. cream formulation against Propionibacterium acnes and Staphylococcus epidermidis. ARTIKEL JURNAL.

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Abstract

Allium sativum L. is one of the plants that has been widely known by the public for a long time and is used as a traditional medicine, one of them as antiacne causes Propionibacterium acnes and Staphylococcus epidermidis [1,2]. Allium sativum L. contains Allicin that may help in inhibits gram-negative or gram-positive bacteria. This study aimed to determine the activity of Allium sativum L. cream formulation with various concentration (25%,35%,45%) against Propionibacterium acnes and Staphylococcus epidermidis. Antibacterial activity was determined by the diameter of the zone of inhibition. Diameter of the zone of inhibition calculated as the difference in diameter of the observed zones and the paper discs. The data of diameter of the zone of inhibition was analyzed with one-way Anova Test. The results showed that Allium sativum L. with all extract concentration had the same effect as negative control in inhibits Propionibacterium acnes and Staphylococcus epidermidis (p>0,05).

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