ANTIDIABETIC ACTIVITY OF POWDER AND ETHANOLIC EXTRACT OF ANTLION (Myrmeleon sp.) ON WISTAR STRAIN WHITE MALE RATS WITH GLUCOSE PRELOAD

Hamidah, Haryanti Rahma and Elza, Sundhani and Nunuk, Aries Nurulita (2016) ANTIDIABETIC ACTIVITY OF POWDER AND ETHANOLIC EXTRACT OF ANTLION (Myrmeleon sp.) ON WISTAR STRAIN WHITE MALE RATS WITH GLUCOSE PRELOAD. PEER REVIEW.

	Text (Peer Review) Antidiabetic Activity of Powder and Ethanolic Extract of Antlion (Myrmeleon Sp.) on Wistar Strain White Male Rats with Glucose Preload.pdf Download (604kB)
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Abstract

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia. It occurs because abnormalities in insulin secretion, insulin action, or both (Gustaviani, 2006). Diabetes treatment is generally done through regular insulin injections and delivery of oral antidiabetic drug such as sulfonylurea class, biguanide, thiazolidinedion and meglitinida which have some side effects like headache, dizziness, nausea, anorexia and permanent organ damage. More over, they are also expensive. People start taking treatment in traditional way natural materials, such as antlion (Myrmeleon sp.,) to lower blood glucose level (Lee et al., 2007). Previous research showed that the young antlion methanolic extract of had the highest inhibitory activity toward α-glucosidase enzyme, was 22.81% (Faiz, 2008). Giving combination of Antlion and bananas for 14 days could decrease blood glucose levels at a dose of 0,01ml / 200g (Tyas 2006). This study has examined the antidiabetic effects of the powder and ethanolic extract of antlion (Myrmeleon sp.) on blood glucose level of Wistar male rats were burdened by glucose.

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